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PART-I
1) Origin and evolution of cell:
a. Evolution of molecules & first cell
b. Evolution from Prokaryotes to Eukaryotes
c. Evolution of single cells to multicellular organisms
2) Introduction to microscopy:
a. Light microscopy principles and applications
b. Compound microscopy
c. Phase contrast microscopy
d. Dark-field microscopy
e. Fluorescence Microscopy
f. Differential interference microscopy
g. Confocal laser scanning microscopy
h. Electron Microscopy
3) Prokaryotic and eukaryotic cells:
a. Sub-cellular structure of prokaryotic and eukaryotic cells
b. Difference between prokaryotic and eukaryotic cells
4) Membrane structure and function:
a. Lipid bilayer
b. Membrane proteins
c. Membrane functions
5) Plasma membrane:
a. Origin of plasma membrane
b. Different models of plasma membrane structure
c. Functions of plasma membrane
6) Cell wall and extracellular matrix:
a. Cell wall composition & structure
b. Functions of cell wall
c. Cell-cell junctions, cell adhesion & extracellular matrix.
7) Structural organization and function of intracellular organelles and organelle biogenesis:
a. Structure & Functions of Nucleus
b. Structure & Functions of plastids
c. Structure & Functions of mitochondria
d. Structure & Functions of endoplasmic reticulum
e. Structure & Functions of Golgi apparatus
f. Structure & Functions of lysosomes, peroxisomes, , vacuoles
PART-II
1) Cytoskeleton:
a. Origin & functions of cytoskeleton
b. Actin & actin binding proteins
c. Myosin & actin
d. Microtubules, Microfilaments & Intermediate filaments
e. Cilia & centrioles
f. Role of cytoskeleton in mobility
2) Cell membrane transport:
a. Principles of membrane transport
b. Active & Passive transport
c. Transporters & their functions
d. Ion-channels
3) Introduction to cell signaling:
a. General principles of signaling
b. Signaling molecules & their receptors
c. Functions of cell surface receptors
d. G-protein coupled receptors
e. Enzyme coupled receptors
f. Pathways of intracellular signal transduction
4) Cell growth, cell cycle and its control:
a. Overview of cell cycle
b. Phase of cell cycle: G1, S phase, M phase, Mitosis & cytokinesis
c. Meiosis
d. Components of cell cycle control system
e. Regulation of cell cycle
5) Cell death &cell renewal:
a. Programmed cell death/Apoptosis
b. Cell renewal: stem cells & maintenance of adult tissues
c. Embryonic stem cells